1.a. Calculate the NNT. Do not worry about a negative or minus sign result. Example: 1.1-2.2 = 1.1 and not -1.1 when calculating the NNT.
1.b. Go to Epocrates Online and determine the cost of Fosamax®, based on one 70mg pill taken orally each week. (Keep in mind that generic Fosamax®, alendronate is now available, so calculate the COPE for both). Also, be aware that Fosamax is available in multiple doses for different routes. Show your actual calculation/math so we can tell what you did right versus wrong.
1.c. What does it cost to prevent one hip fracture over 3 years, using the COPE calculation posted in the chapter?
1.d. Is this more meaningful than just talking about a 50% reduction in hip fractures?
2.a. What did you get?
2.b. Take a snapshot of the result and include it in the lab report.
2.c. Can you see how a large organization might use EBM, a calculator and drug costs to decide on the best therapy? Explain your observation.
2.d. Could this be automatically calculated with an EHR?
3.a. How would you take advantage of this data?
3.e. Sort asthmatics by age. How many are younger than 18?
3.f. What percentage of all asthmatics are younger than 18?
3.g. What percentage of all asthmatics have visited the emergency room (ER)? These might be your most severe OR least compliant.
3.h. What percentage of all asthmatics are seen more frequently in the clinic (frequent flyers) than in ER, according to the spreadsheet?
3.i. Are patients visiting clinic more frequently are on more medications than patients visiting ER (which might mean they are more severe or more compliant)?
3.j. What percentage of patients that visited the emergency room (ER) were on inhaled corticosteroids (ICS)?
4.c. Take a snapshot of the final filtered PubMed search results.
4.d. Take a snapshot of the clinical queries search results and submit it as part of your lab report for the day.