Explain how the authors use their data to link Hp1bp3 to memory capacity in humans?

Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging

(1%) The authors refer to CFM testing, what does this acronym stand for and describe what it helps the authors test in this study?

(1%) Explain how the authors use their data to make the connection between Hp1bp3 and Alzheimer’s disease?

(1%) Explain how the authors use their data to link Hp1bp3 to memory capacity in humans?

(1%) Why did the authors use the BXD mice in this study?

(1%) How did the authors use functional validation to confirm their hypothesized link between Hp1bp3 and cognitive function.