Tag Archives: bleomycins

How does this model complex damage tumour DNA, and does the type of amino acid used to make this model complex affect its ability to damage DNA?Discuss

In the experiment you used a complex, whose full name is (5-amino-5-methyl-3,7-diazanonanedioate)copper(II), to model the active site of a bleomycin. This complex was made by first reacting copper(II) ions, glycine and nitroethane (i), followed by reduction (ii) of the nitro group, -NO2, to amine, -NH2. Similar reactions can be carried out using other amino acids […]