Describe the conceptual problems Polly Matzinger identified in the classical ‘self/non-self’ model of adaptive immune activation. How did she modify this model to address conceptual problems?

Select two of the T-helper subsets of CD4+ T cells and discuss their influence on the development of immune responses. (300 words) Describe the conceptual problems Polly Matzinger identified in the classical ‘self/non-self’ model of adaptive immune activation. How did she modify this model to address conceptual problems? (150 words) Select a vaccine of your […]