Write a short paragraph explaining why the tetracyclines have been more successful as a class of drugs against MRSA than the beta-lactams.

MRSA is a highly resistant hospital-acquired infection that is extremely resistant to the action of beta-lactam antibiotics. There is only one cephalosporin that is effective against MRSA, and none of the penicillins or carbapenems have activity against MRSA. In contrast to the beta-lactams, the tetracycline class of antibiotics has shown much promise recently against MRSA. […]