Tag Archives: Enterohemorrhagic

What would happen to the enzyme’s affinity for cyclic AMP if the enzyme’s active site had a missense mutation that changed the Serine residues (orange and dark green) to Threonine?  Briefly explain your answer.

Protein Folding Part I:  Protein Folding The shiga-like toxin (ST) is a protein-based toxin produced by the bacterium Enterohemorrhagic Escherichia coli (EHEC), which is the causative agent responsible for most cases of bloody diarrhea.  Believe it or not, much of the disease symptoms associated with EHEC infection derives from the cytotoxic effects of ST, whose […]