What are your thoughts on the Two-Hit Theory?

The Two-Hit theory The Two-Hit theory is very interesting, look it up if you are unfamiliar with it. What are your thoughts on the Two-Hit Theory? Knudson’s “Two-Hit” Theory of Cancer Causation | Fox Chase Cancer Center – Philadelphia PA An interesting website: http://genetics.thetech.org/ask/ask136 This was an interesting way of explaining this: https://mymodernmet.com/know-your-lemons-update/